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Symbol Name ID |
Gpx4
glutathione peroxidase 4 MGI:104767 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Uterine leiomyosarcoma |
| Disease(s) Associated with GPX4 | |
| colorectal cancer |
| Mouse Phenotypes | reproductive system phenotype |
abnormal sperm midpiece morphology |
abnormal sperm mitochondrial sheath morphology |
abnormal sperm principal piece morphology |
hairpin sperm flagellum |
kinked sperm flagellum |
oligozoospermia |
abnormal sperm head morphology |
abnormal male germ cell morphology |
decreased male germ cell number |
abnormal sperm motility |
asthenozoospermia |
decreased testis weight |
small testis |
hydrometra |
empty decidua capsularis |
decreased litter size |
male infertility |
reduced male fertility |
impaired fertilization |
decreased fertilization frequency |
abnormal sperm physiology |
|
| Availability | Mouse Genotype | ||||||||||||||||||||||
| Gpx4tm1Marc/Gpx4tm1Marc | * | ||||||||||||||||||||||
| Gpx4tm3Marc/Gpx4tm3Marc | * | ||||||||||||||||||||||
| Gpx4tm4Marc/Gpx4tm4Marc | |||||||||||||||||||||||
| Gpx4tm1.1(KOMP)Vlcg/Gpx4+ | |||||||||||||||||||||||
| Gpx4tm4Marc/Gpx4+ | |||||||||||||||||||||||
| Gpx4tm1Yana/Gpx4tm1Yana Tg(Gpx4)#Yana/0 Tg(Pgk2-cre)24Shb/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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